PXD018597-1
PXD018597 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Myeloid PTEN promotes chemotherapy-induced NLRP3 inflammasome activation and antitumor immunity |
| Description | In this study, we found that myeloid PTEN can determine chemotherapy responsiveness by promoting NLRP3-dependent antitumor immunity and suggest that it might be a potential biomarker to predict the chemotherapy responses and manipulating NLRP3/IL-1might be able to overcome the chemotherapy resistance in PTEN-loss patients. |
| HostingRepository | iProX |
| AnnounceDate | 2020-04-16 |
| AnnouncementXML | Submission_2020-04-16_04:58:14.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yi Huang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | phosphorylated residue |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2020-04-16 04:54:50 | ID requested | |
| ⏵ 1 | 2020-04-16 04:58:15 | announced | |
| 2 | 2020-11-24 22:05:10 | announced | 2020-11-25: Update publication information |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Myeloid PTEN, chemotherapy, NLRP3 inflammasome |
Contact List
| Rongbin Zhou | |
|---|---|
| contact affiliation | University of Science and Technology of China |
| contact email | zrb1980@ustc.edu.cn |
| lab head | |
| Yi Huang | |
| contact affiliation | University of Science and Technology of China |
| contact email | hy527@mail.ustc.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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