PXD018597-1
PXD018597 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Myeloid PTEN promotes chemotherapy-induced NLRP3 inflammasome activation and antitumor immunity |
Description | In this study, we found that myeloid PTEN can determine chemotherapy responsiveness by promoting NLRP3-dependent antitumor immunity and suggest that it might be a potential biomarker to predict the chemotherapy responses and manipulating NLRP3/IL-1might be able to overcome the chemotherapy resistance in PTEN-loss patients. |
HostingRepository | iProX |
AnnounceDate | 2020-04-16 |
AnnouncementXML | Submission_2020-04-16_04:58:14.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yi Huang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2020-04-16 04:54:50 | ID requested | |
⏵ 1 | 2020-04-16 04:58:15 | announced | |
2 | 2020-11-24 22:05:10 | announced | 2020-11-25: Update publication information |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Myeloid PTEN, chemotherapy, NLRP3 inflammasome |
Contact List
Rongbin Zhou | |
---|---|
contact affiliation | University of Science and Technology of China |
contact email | zrb1980@ustc.edu.cn |
lab head | |
Yi Huang | |
contact affiliation | University of Science and Technology of China |
contact email | hy527@mail.ustc.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |