PXD016394-2

PXD016394 is an original dataset announced via ProteomeXchange.

Title	The GTPase Rab39a matures phagosomes into MHC-I antigen-presenting compartments.
Description	We have found Rab39a to be important in dendritic cells to promote antigen crosspresentation. As Rab39a is a Rab GTPase, we sought to determine how it influenced the contents of phagosomes. Thus we used SILAC using Rab39a CRISPR KO or reconstituted cells to determine phagosomal protein differences using a proteomics based approach.
HostingRepository	PRIDE
AnnounceDate	2019-12-11
AnnouncementXML	Submission_2019-12-11_05:29:57.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD016394
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Freidrich Cruz
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	Label:13C(6)15N(2); Label:13C(6)15N(4); Oxidation; Acetyl; Carbamidomethyl; Gln->pyro-Glu
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-11-22 01:10:27	ID requested
1	2019-12-11 02:11:47	announced
⏵ 2	2019-12-11 05:29:59	announced	2019-12-11: Updated project metadata.

Dataset with its publication pending

curator keyword: Biological

submitter keyword: Rab39a, dendritic cell, phagosomes

Kenneth Rock
contact affiliation	UMASS Medical School, Department of Pathology
contact email	Kenneth.Rock@umassmed.edu
lab head
Freidrich Cruz
contact affiliation	UMASS Medical School
contact email	freidrich.cruz@live.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/12/PXD016394

PRIDE project URI

• PRIDE
  1. PXD016394
     1. Label: PRIDE project
     2. Name: The GTPase Rab39a matures phagosomes into MHC-I antigen-presenting compartments.