PXD016394 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The GTPase Rab39a matures phagosomes into MHC-I antigen-presenting compartments. |
Description | We have found Rab39a to be important in dendritic cells to promote antigen crosspresentation. As Rab39a is a Rab GTPase, we sought to determine how it influenced the contents of phagosomes. Thus we used SILAC using Rab39a CRISPR KO or reconstituted cells to determine phagosomal protein differences using a proteomics based approach. |
HostingRepository | PRIDE |
AnnounceDate | 2019-12-11 |
AnnouncementXML | Submission_2019-12-11_02:11:45.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD016394 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Freidrich Cruz |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | Label:13C(6)15N(2); Label:13C(6)15N(4); Oxidation; Acetyl; Carbamidomethyl; Gln->pyro-Glu |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-11-22 01:10:27 | ID requested | |
⏵ 1 | 2019-12-11 02:11:47 | announced | |
2 | 2019-12-11 05:29:59 | announced | 2019-12-11: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Rab39a, dendritic cell, phagosomes |
Contact List
Kenneth Rock |
contact affiliation | UMASS Medical School, Department of Pathology |
contact email | Kenneth.Rock@umassmed.edu |
lab head | |
Freidrich Cruz |
contact affiliation | UMASS Medical School |
contact email | freidrich.cruz@live.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD016394
- Label: PRIDE project
- Name: The GTPase Rab39a matures phagosomes into MHC-I antigen-presenting compartments.