PXD015100 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The kinetoplastid outer kinetochore |
| Description | In spite of their universal function, the composition of kinetochores differs greatly across eukaryotes. Trypanosomes and other organisms Kinetoplastida diverged very early during eukaryotic radiation from the line that includes animals and fungi, and build kinetochores with very little detectable homology to models. However, the full extent of the trypanosome kinetochore is unclear. Here, we have used quantitative proteomics from multiple start points to define the interaction network of the kinetoplastid kinetochore-interacting proteins (KKIPs). These data identify new components of the kinetochore and define a stable 9-protein complex distal to KKIP1 that forms the majority of the kinetoplastid outer kinetochore. |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-10-22 |
| AnnouncementXML | Submission_2024-10-22_05:02:41.186.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Bill Wickstead |
| SpeciesList | scientific name: Trypanosoma brucei; NCBI TaxID: 5691; |
| ModificationList | monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue; deamidated residue |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2019-08-21 00:59:24 | ID requested | |
| 1 | 2020-04-27 08:15:10 | announced | |
| ⏵ 2 | 2024-10-22 05:02:41 | announced | 2024-10-22: Updated project metadata. |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Kinetochore, Chromosome segregation, Kinetoplastida, Trypanosoma, Mitosis |
Contact List
| Bill Wickstead |
|---|
| contact affiliation | School of Life Sciences University of Nottingham Nottingham UK |
| contact email | bill.wickstead@nottingham.ac.uk |
| lab head | |
| Bill Wickstead |
|---|
| contact affiliation | School of Life Sciences, University of Nottingham |
| contact email | bill.wickstead@nottingham.ac.uk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/04/PXD015100 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD015100
- Label: PRIDE project
- Name: The kinetoplastid outer kinetochore
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