PXD015100-1

PXD015100 is an original dataset announced via ProteomeXchange.

Title	The kinetoplastid outer kinetochore
Description	In spite of their universal function, the composition of kinetochores differs greatly across eukaryotes. Trypanosomes and other organisms Kinetoplastida diverged very early during eukaryotic radiation from the line that includes animals and fungi, and build kinetochores with very little detectable homology to models. However, the full extent of the trypanosome kinetochore is unclear. Here, we have used quantitative proteomics from multiple start points to define the interaction network of the kinetoplastid kinetochore-interacting proteins (KKIPs). These data identify new components of the kinetochore and define a stable 9-protein complex distal to KKIP1 that forms the majority of the kinetoplastid outer kinetochore.
HostingRepository	PRIDE
AnnounceDate	2020-04-27
AnnouncementXML	Submission_2020-04-27_08:15:09.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Bill Wickstead
SpeciesList	scientific name: Trypanosoma brucei; NCBI TaxID: 5691;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2019-08-21 00:59:24	ID requested
⏵ 1	2020-04-27 08:15:10	announced
2	2024-10-22 05:02:41	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Kinetochore, Mitosis, Chromosome segregation, Trypanosoma, Kinetoplastida

Bill Wickstead
contact affiliation	School of Life Sciences University of Nottingham Nottingham UK
contact email	bill.wickstead@nottingham.ac.uk
lab head
Bill Wickstead
contact affiliation	School of Life Sciences, University of Nottingham
contact email	bill.wickstead@nottingham.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/04/PXD015100

PRIDE project URI

• PRIDE
  1. PXD015100
     1. Label: PRIDE project
     2. Name: The kinetoplastid outer kinetochore