PXD005815-3

PXD005815 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Phospho-proteome of obese mice brains
Description	This study aims to investigate changes in phospho-proteomic levels of mice brain. The focus of the study is the phospho-proteome because phoshorylation is one of the key post-translational modification, which regulates many biological processes. In particular we wanted to inspect the effects of two different kinds of diet (hyperglycemic diet and high-fat diet) compaired with a conventional chow diet. We have found interesting changes in the phosphorylation state of several proteins involved in nervous system development as well as vesicle trafficking and cytoskeleton remodelling.We hope that our study can contribute to elucidating the impact that obesity could have on the brain phospho-proteome.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:28:12.306.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD005815
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Valentina Siino
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-01-31 05:32:41	ID requested
1	2018-06-10 09:32:12	announced
2	2018-06-14 08:37:47	announced	Updated publication reference for PubMed record(s): 29886190.
⏵ 3	2024-10-22 04:28:15	announced	2024-10-22: Updated project metadata.

Publication List

Siino V, Amato A, Di Salvo F, Caldara GF, Filogamo M, James P, Vasto S, Impact of diet-induced obesity on the mouse brain phosphoproteome. J Nutr Biochem, 58():102-109(2018) [pubmed]
10.6019/PXD005815;
10.1016/j.jnutbio.2018.04.015;

Siino V, Amato A, Di Salvo F, Caldara GF, Filogamo M, James P, Vasto S, Impact of diet-induced obesity on the mouse brain phosphoproteome. J Nutr Biochem, 58():102-109(2018) [pubmed]

10.6019/PXD005815;

10.1016/j.jnutbio.2018.04.015;

Keyword List

curator keyword: Biological, Biomedical
submitter keyword: obesity, diet, CNS development, mice brains,Phospho-proteome

curator keyword: Biological, Biomedical

submitter keyword: obesity, diet, CNS development, mice brains,Phospho-proteome

Contact List

Peter James
contact affiliation	Lund University, Sweden
contact email	peter.james@immun.lth.se
lab head
Valentina Siino
contact affiliation	Lund University
contact email	valentina.siino@immun.lth.se
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/06/PXD005815
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/06/PXD005815

PRIDE project URI

Repository Record List

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