PXD002869-1

PXD002869 is an original dataset announced via ProteomeXchange.

Title	Enterococcus faecalis V583
Description	Genome-scale models represent the link between an organism's genetic information and experimentally observable biological phenotypes. They facilitate metabolic engineering and the discovery of network properties such as the identification of novel drug targets. Most commonly, metabolite consumption data is used to limit the solution space, sometimes in combination with gene expression data. However, information about gene expression only poorly correlates with the abundance of the respective proteins within the cell. As such, we developed a method to map and integrate the whole-cell proteome into genome-scale models on the example of lactic acid bacteria (LAB). To the best of our knowledge, this work represents the first effort to integrate proteome data into genome-scale models on such a scale .
HostingRepository	PRIDE
AnnounceDate	2016-12-07
AnnouncementXML	Submission_2016-12-07_05:11:20.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ben Collins
SpeciesList	scientific name: Enterococcus faecalis (Streptococcus faecalis); NCBI TaxID: 1351;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2015-09-07 04:40:51	ID requested
⏵ 1	2016-12-07 05:11:21	announced
2	2020-03-12 03:38:48	announced	2020-03-12: Updated project metadata.
3	2023-11-14 08:48:51	announced	2023-11-14: Updated project metadata.

10.1038/npjsba.2016.17;

curator keyword: Biological

submitter keyword: EFV583, SWATH, pH_shift

Ursula Kummer
contact affiliation	Department of Modeling of Biological Processes COS, Heidelberg University
contact email	ursula.kummer@bioquant.uni-heidelberg.de
lab head
Ben Collins
contact affiliation	ETH Zurich
contact email	collins@imsb.biol.ethz.ch
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/12/PXD002869

PRIDE project URI

• PRIDE
  1. PXD002869
     1. Label: PRIDE project
     2. Name: Enterococcus faecalis V583