<<< Full experiment listing

PXD021549

PXD021549 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHidden Proteome of Synaptic Vesicles in the Mammalian Brain
Descriptioncurrent synapse proteomics are restricted to “average” composition of abundant synaptic proteins. Here we performed a subcellular proteomic workflow that could identify and quantify the deep proteome of synaptic vesicles purified from rat whole brain, including previously missing proteins present in a small percentage of central synapses. This synaptic vesicle proteome newly detected many proteins of physiological and pathological relevance particularly in low abundance range, thus providing a resource for future investigations on diversified synaptic functions and neuronal dysfunctions. Raw data from 3 replicates of synaptosomes (P2') and 3 replicates of SV are deposited here. Each replicate coming from 24 fractions from a peptide fractionation step in the workflow.
HostingRepositoryjPOST
AnnounceDate2020-12-31
AnnouncementXMLSubmission_2022-09-18_02:55:04.638.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZacharie Taoufiq
SpeciesList scientific name: Rattus norvegicus albus; NCBI TaxID: 947987;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-09-17 18:03:53ID requested
12020-12-30 07:00:09announced
22021-02-04 17:09:23announced2021-02-04: Updated FTP location.
32022-09-18 02:55:05announced2022-09-18: Updated FTP location.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: rat, Synapse, deep proteomics, synaptic vesicles, neurotransmission
Contact List
Zacharie Taoufiq
lab head
Zacharie Taoufiq
contact affiliationOkinawa Institute of Science and Technology, Graduate University
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000968/