PXD019995-1

PXD019995 is an original dataset announced via ProteomeXchange.

Title	The effect of skyrin in normoxia and hypoxia on HCT 116 cell line
Description	Skyrin is a plant secondary metabolite from Hypericum genus with potential in anticancer therapy. It is structurally very similar to hypericin. The mechanism of its action in normoxia as well as in hypoxia, when cells are expressing multiple adaptive mechanisms connected to poor prognosis, could be very interesting. To achieve it, label-free comparative proteomic analysis of HCT 116 cell lines samples was performed.
HostingRepository	PRIDE
AnnounceDate	2021-04-08
AnnouncementXML	Submission_2021-04-07_22:51:29.252.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	David Potesil
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-06-24 07:00:05	ID requested
⏵ 1	2021-04-07 22:51:29	announced
2	2021-05-03 21:52:04	announced	2021-05-04: Updated publication reference for PubMed record(s): 33916015.
3	2024-10-22 05:20:57	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Skyrin, hypoxia, colorectal cancer, LC-MS/MS, label-free

Zbynek Zdrahal
contact affiliation	Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic
contact email	zdrahal@sci.muni.cz
lab head
David Potesil
contact affiliation	Proteomics Core Facility and Research Group Proteomics CEITEC-MU Masaryk University Brno, Czech Republic
contact email	david.potesil@ceitec.muni.cz
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD019995

PRIDE project URI

• PRIDE
  1. PXD019995
     1. Label: PRIDE project
     2. Name: The effect of skyrin in normoxia and hypoxia on HCT 116 cell line