PXD019995 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The effect of skyrin in normoxia and hypoxia on HCT 116 cell line |
Description | Skyrin is a plant secondary metabolite from Hypericum genus with potential in anticancer therapy. It is structurally very similar to hypericin. The mechanism of its action in normoxia as well as in hypoxia, when cells are expressing multiple adaptive mechanisms connected to poor prognosis, could be very interesting. To achieve it, label-free comparative proteomic analysis of HCT 116 cell lines samples was performed. |
HostingRepository | PRIDE |
AnnounceDate | 2021-04-08 |
AnnouncementXML | Submission_2021-05-03_21:52:03.444.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | David Potesil |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-06-24 07:00:05 | ID requested | |
1 | 2021-04-07 22:51:29 | announced | |
⏵ 2 | 2021-05-03 21:52:04 | announced | 2021-05-04: Updated publication reference for PubMed record(s): 33916015. |
Publication List
Babin, č, á, k M, Jend, ž, elovsk, ý R, Ko, š, uth J, Majern, í, k M, Vargov, á J, Mikul, á, š, ek K, Zdr, á, hal Z, Fedoro, č, ko P, spp. Cancers (Basel), 13(7):(2021) [pubmed] |
Keyword List
submitter keyword: Skyrin, hypoxia, colorectal cancer, LC-MS/MS, label-free |
Contact List
Zbynek Zdrahal |
contact affiliation | Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic |
contact email | zdrahal@sci.muni.cz |
lab head | |
David Potesil |
contact affiliation | Proteomics Core Facility and Research Group Proteomics CEITEC-MU Masaryk University Brno, Czech Republic |
contact email | david.potesil@ceitec.muni.cz |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD019995 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD019995
- Label: PRIDE project
- Name: The effect of skyrin in normoxia and hypoxia on HCT 116 cell line