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PXD019995 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe effect of skyrin in normoxia and hypoxia on HCT 116 cell line
DescriptionSkyrin is a plant secondary metabolite from Hypericum genus with potential in anticancer therapy. It is structurally very similar to hypericin. The mechanism of its action in normoxia as well as in hypoxia, when cells are expressing multiple adaptive mechanisms connected to poor prognosis, could be very interesting. To achieve it, label-free comparative proteomic analysis of HCT 116 cell lines samples was performed.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDavid Potesil
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-24 07:00:05ID requested
12021-04-07 22:51:29announced
22021-05-03 21:52:04announced2021-05-04: Updated publication reference for PubMed record(s): 33916015.
Publication List
Babinčák M, Jendželovský R, Košuth J, Majerník M, Vargová J, Mikulášek K, Zdráhal Z, Fedoročko P, spp. Cancers (Basel), 13(7):(2021) [pubmed]
Keyword List
submitter keyword: Skyrin, hypoxia, colorectal cancer, LC-MS/MS, label-free
Contact List
Zbynek Zdrahal
contact affiliationProteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic
contact emailzdrahal@sci.muni.cz
lab head
David Potesil
contact affiliationProteomics Core Facility and Research Group Proteomics CEITEC-MU Masaryk University Brno, Czech Republic
contact emaildavid.potesil@ceitec.muni.cz
dataset submitter
Full Dataset Link List
Dataset FTP location
PRIDE project URI
Repository Record List
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