PXD015670 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Identification of JARID2/PRC2 interactome in human embryonic stem cells |
| Description | JARID2 is an integral subunit of the chromatin modifier PRC2 (Polycomb Repressive Complex 2). PRC2 methylates lysine 27 in histone H3 and is required for human development. Mutaitons of PRC2 subunits have been frequently found in a variety of adult and pediatric cancer, suggesting that PRC2 critically regulates normal and cancer development. The goal of this project is to identify new regulator or co-factors of PRC2 and study their molecular interactions and activities in order to better understand function and regulation of PRC2 in normal and cancer development. |
| HostingRepository | PRIDE |
| AnnounceDate | 2020-08-04 |
| AnnouncementXML | Submission_2020-08-03_22:15:02.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Vishwajeeth Pagala |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion; LTQ Orbitrap Elite |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2019-10-02 01:11:48 | ID requested | |
| ⏵ 1 | 2020-08-03 22:15:02 | announced | |
| 2 | 2020-09-11 03:43:28 | announced | 2020-09-11: Updated publication reference for PubMed record(s): 32792512. |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: human embryonic stem cells |
| pluripotency |
| JARID2 |
| PRC2 |
| proteomics |
| proteome |
Contact List
| Jamy Peng |
|---|
| contact affiliation | St. Jude Children's Research Hospital, Developmental Neurobiology |
| contact email | Jamy.peng@stjude.org |
| lab head | |
| Vishwajeeth Pagala |
|---|
| contact affiliation | St. Jude Children's Research Hospital |
| contact email | vishwajeeth.pagala@stjude.org |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/08/PXD015670 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD015670
- Label: PRIDE project
- Name: Identification of JARID2/PRC2 interactome in human embryonic stem cells
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