PXD008795 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Peptidomics of Human Hypothalamic neurons |
Description | The study of peptide secretion, and identifying its control requires the use of ELISAs for measuring their levels pre and post stimulation. In place of ELISA's an LC-MS methdology was developed first to identify the correct peptides generated by the neurons, which could then be used to measure the peptide products by targetted LC-MS analysis. The Extraction was also performed on human hypothalamic tissue obtained from a tissue bank. Samples were analysed by nano LC-MS, and searched using Peaks 8.5. |
HostingRepository | PRIDE |
AnnounceDate | 2018-08-22 |
AnnouncementXML | Submission_2018-08-22_08:38:24.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD008795 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Richard Kay |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | Amidated; Oxidation; Acetyl; Carbamidomethyl; Gln->pyro-Glu |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-01-30 05:50:50 | ID requested | |
⏵ 1 | 2018-08-22 08:38:25 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
curator keyword: Biological, Biomedical |
submitter keyword: Hypothalamic neurons, POMC, Peptidomics |
Contact List
Florian Merkle |
contact affiliation | University of Cambridge |
contact email | fm436@medschl.cam.ac.uk |
lab head | |
Richard Kay |
contact affiliation | University of Cambridge |
contact email | rgk27@medschl.cam.ac.uk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD008795
- Label: PRIDE project
- Name: Peptidomics of Human Hypothalamic neurons