PXD003815 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Quantitative proteome profiling of Leishmania donovani after hypericin treatment |
Description | Hypericin, a novel inhibitor of spermidine synthase of Leishmania donovani, has been found to cause necrotic like death of the parasite. Hypericin treatment has indicated the importance of spermidine in pathways other than redox metabolism of Leishmania parasite. We have used label free quantitative proteomics approach to compare the alteration in expression of proteins in untreated and hypericin treated Leishmania promastigotes. |
HostingRepository | PRIDE |
AnnounceDate | 2016-04-21 |
AnnouncementXML | Submission_2016-04-29_02:38:36.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD003815 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Shalini Singh |
SpeciesList | scientific name: Leishmania donovani; NCBI TaxID: 5661; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitap Discovery |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-03-18 05:57:44 | ID requested | |
1 | 2016-04-21 03:16:29 | announced | |
⏵ 2 | 2016-04-29 02:38:37 | announced | Updated publication reference for PubMed record(s): 27123864. |
Publication List
Singh S, Dubey VK, Quantitative Proteome Analysis of Leishmania donovani under Spermidine Starvation. PLoS One, 11(4):e0154262(2016) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: Leishmania donovani, Label free proteome quantitaion, hypericin |
Contact List
Professsor Vikash Kumar Dubey |
contact affiliation | Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, India |
contact email | vdubey@iitg.ernet.in |
lab head | |
Shalini Singh |
contact affiliation | Indian Institute of Technology Guwahati, Assam, India |
contact email | shalini.s@iitg.ernet.in |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/04/PXD003815 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD003815
- Label: PRIDE project
- Name: Quantitative proteome profiling of Leishmania donovani after hypericin treatment