PXD003815-1

PXD003815 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteome profiling of Leishmania donovani after hypericin treatment
Description	Hypericin, a novel inhibitor of spermidine synthase of Leishmania donovani, has been found to cause necrotic like death of the parasite. Hypericin treatment has indicated the importance of spermidine in pathways other than redox metabolism of Leishmania parasite. We have used label free quantitative proteomics approach to compare the alteration in expression of proteins in untreated and hypericin treated Leishmania promastigotes.
HostingRepository	PRIDE
AnnounceDate	2016-04-21
AnnouncementXML	Submission_2016-04-21_03:16:29.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD003815
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Shalini Singh
SpeciesList	scientific name: Leishmania donovani; NCBI TaxID: 5661;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitap Discovery

Revision	Datetime	Status	ChangeLog Entry
0	2016-03-18 05:57:44	ID requested
⏵ 1	2016-04-21 03:16:29	announced
2	2016-04-29 02:38:37	announced	Updated publication reference for PubMed record(s): 27123864.

Dataset with its publication pending

curator keyword: Biomedical

submitter keyword: Leishmania donovani, Label free proteome quantitaion, hypericin

Professsor Vikash Kumar Dubey
contact affiliation	Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, India
contact email	vdubey@iitg.ernet.in
lab head
Shalini Singh
contact affiliation	Indian Institute of Technology Guwahati, Assam, India
contact email	shalini.s@iitg.ernet.in
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/04/PXD003815

PRIDE project URI

• PRIDE
  1. PXD003815
     1. Label: PRIDE project
     2. Name: Quantitative proteome profiling of Leishmania donovani after hypericin treatment