PXD002570 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The extracellular vesicles of the helminth pathogen, Fasciola hepatica: biogenesis pathways and cargo molecules involved in parasite pathogenesis |
Description | We reveal that whilst the molecular “machinery” required for EV biogenesis is constitutively expressed across the intra-mammalian development stages of the parasite, the cargo molecules packaged within the EVs are regulated, most likely to facilitate the parasites migration through host tissue and to counteract host immune attack. |
HostingRepository | PRIDE |
AnnounceDate | 2015-10-14 |
AnnouncementXML | Submission_2015-10-23_03:16:45.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD002570 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Luz Valero |
SpeciesList | scientific name: Fasciola hepatica (Liver fluke); NCBI TaxID: 6192; |
ModificationList | Oxidation; Carbamidomethyl; Deamidated |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2015-07-21 01:08:09 | ID requested | |
1 | 2015-10-14 03:52:44 | announced | |
⏵ 2 | 2015-10-23 03:16:46 | announced | Updated publication reference for PubMed record(s): 26486420. |
Publication List
Cwiklinski K, de la Torre-Escudero E, Trelis M, Bernal D, Dufresne PJ, Brennan GP, O'Neill S, Tort J, Paterson S, Marcilla A, Dalton JP, Robinson MW, The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis. Mol Cell Proteomics, 14(12):3258-73(2015) [pubmed] |
Keyword List
curator keyword: Biomedical, Biological |
submitter keyword: Helminth, Fasciola, proteomics, transcriptomics, extracellular vesicle, exosome, secretome |
Contact List
Antonio Marcilla |
contact affiliation | Departmento de Bioquíimica y Biologíia Molecular, Universitat de Valèencia, Burjassot, Valencia, Spain |
contact email | Antonio.Marcilla@uv.es |
lab head | |
Luz Valero |
contact affiliation | Universitat de Valencia |
contact email | mluz.valero@uv.es |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2015/10/PXD002570 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD002570
- Label: PRIDE project
- Name: The extracellular vesicles of the helminth pathogen, Fasciola hepatica: biogenesis pathways and cargo molecules involved in parasite pathogenesis