PXD002570

PXD002570 is an original dataset announced via ProteomeXchange.

Title	The extracellular vesicles of the helminth pathogen, Fasciola hepatica: biogenesis pathways and cargo molecules involved in parasite pathogenesis
Description	We reveal that whilst the molecular “machinery” required for EV biogenesis is constitutively expressed across the intra-mammalian development stages of the parasite, the cargo molecules packaged within the EVs are regulated, most likely to facilitate the parasites migration through host tissue and to counteract host immune attack.
HostingRepository	PRIDE
AnnounceDate	2015-10-14
AnnouncementXML	Submission_2015-10-23_03:16:45.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD002570
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Luz Valero
SpeciesList	scientific name: Fasciola hepatica (Liver fluke); NCBI TaxID: 6192;
ModificationList	Oxidation; Carbamidomethyl; Deamidated
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2015-07-21 01:08:09	ID requested
1	2015-10-14 03:52:44	announced
⏵ 2	2015-10-23 03:16:46	announced	Updated publication reference for PubMed record(s): 26486420.

Cwiklinski K, de la Torre-Escudero E, Trelis M, Bernal D, Dufresne PJ, Brennan GP, O'Neill S, Tort J, Paterson S, Marcilla A, Dalton JP, Robinson MW, The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis. Mol Cell Proteomics, 14(12):3258-73(2015) [pubmed]

curator keyword: Biomedical, Biological

submitter keyword: Helminth, Fasciola, proteomics, transcriptomics, extracellular vesicle, exosome, secretome

Antonio Marcilla
contact affiliation	Departmento de Bioquíimica y Biologíia Molecular, Universitat de Valèencia, Burjassot, Valencia, Spain
contact email	Antonio.Marcilla@uv.es
lab head
Luz Valero
contact affiliation	Universitat de Valencia
contact email	mluz.valero@uv.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2015/10/PXD002570

PRIDE project URI

• PRIDE
  1. PXD002570
     1. Label: PRIDE project
     2. Name: The extracellular vesicles of the helminth pathogen, Fasciola hepatica: biogenesis pathways and cargo molecules involved in parasite pathogenesis