PXD000092

PXD000092 is an original dataset announced via ProteomeXchange.

Title	Human Chr18. 25 light, 17 heavy synth peps for 21 prots (Zgoda, et al.)
Description	Dataset QC1 was acquired to elaborate the transition groups for the proteotypic peptides of 21 human proteins encoded by chromosome 18. Preliminary transition groups were extracted from the results of MRM scouting of depleted plasma and liver and organized into 9 MRM assays by groups named A to E with least overlapping of RT-window of proteotypic peptides separately for light (L) and heavy (H). Decoy transitions were generated for each assay by ADD_RANDOM algorithm of mGen. Data acquisition for each assay was conducted using the synthetic peptide mixtures in five technical runs on the triple-quadrupole mass-spectrometer.
HostingRepository	PeptideAtlas
AnnounceDate	2014-03-12
AnnouncementXML	Submission_2014-03-12_13:28:12.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Aleksey Filimonov
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	6x(13)C labeled L-leucine
Instrument	Agilent 6410 Triple Quad

Revision	Datetime	Status	ChangeLog Entry
0	2012-12-10 17:29:58	ID requested
1	2012-12-10 17:31:51	announced
2	2012-12-11 11:42:52	announced	missing
3	2012-12-11 17:14:17	announced	missing
⏵ 4	2014-03-12 13:28:12	announced	update LabHead

Zgoda VG, Kopylov AT, Tikhonova OV, Moisa AA, Pyndyk NV, Farafonova TE, Novikova SE, Lisitsa AV, Ponomarenko EA, Poverennaya EV, Radko SP, Khmeleva SA, Kurbatov LK, Filimonov AD, Bogolyubova NA, Ilgisonis EV, Chernobrovkin AL, Ivanov AS, Medvedev AE, Mezentsev YV, Moshkovskii SA, Naryzhny SN, Ilina EN, Kostrjukova ES, Alexeev DG, Tyakht AV, Govorun VM, Archakov AI, Chromosome 18 transcriptome profiling and targeted proteome mapping in depleted plasma, liver tissue and HepG2 cells. J Proteome Res, 12(1):123-34(2013) [pubmed]

curator keyword: selected reaction monitoring, SRM, targeted

Aleksey Filimonov
contact affiliation	IMSB
contact email	filimonov.a.d@gmail.com
dataset submitter
Alexander Archakov
contact affiliation	IMSB
contact email	alexander.archakov@ibmc.msk.ru
lab head

PeptideAtlas dataset URI

PASSEL experiment URI

PASSEL transition group browser URI