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PXD000092

DataSet Summary

  • HostingRepository: PeptideAtlas
  • AnnounceDate: 2014-03-12
  • AnnouncementXML: Submission_2014-03-12_13:28:12.xml
  • DigitalObjectIdentifier:
  • ReviewLevel: Peer-reviewed dataset
  • DatasetOrigin: Original data
  • RepositorySupport: Supported dataset by repository
  • PrimarySubmitter: Aleksey Filimonov
  • Title: Human Chr18. 25 light, 17 heavy synth peps for 21 prots (Zgoda, et al.)
  • Description: Dataset QC1 was acquired to elaborate the transition groups for the proteotypic peptides of 21 human proteins encoded by chromosome 18. Preliminary transition groups were extracted from the results of MRM scouting of depleted plasma and liver and organized into 9 MRM assays by groups named A to E with least overlapping of RT-window of proteotypic peptides separately for light (L) and heavy (H). Decoy transitions were generated for each assay by ADD_RANDOM algorithm of mGen. Data acquisition for each assay was conducted using the synthetic peptide mixtures in five technical runs on the triple-quadrupole mass-spectrometer.
  • SpeciesList: scientific name: Homo sapiens; NCBI TaxID: 9606;
  • ModificationList: 6x(13)C labeled L-leucine
  • Instrument: Agilent 6410 Triple Quad

Dataset History

VersionDatetimeStatusChangeLog Entry
02012-12-10 17:29:58ID requested
12012-12-10 17:31:51announced
22012-12-11 11:42:52announcedmissing
32012-12-11 17:14:17announcedmissing
42014-03-12 13:28:12announcedupdate LabHead

Publication List

  1. Zgoda VG, Kopylov AT, Tikhonova OV, Moisa AA, Pyndyk NV, Farafonova TE, Novikova SE, Lisitsa AV, Ponomarenko EA, Poverennaya EV, Radko SP, Khmeleva SA, Kurbatov LK, Filimonov AD, Bogolyubova NA, Ilgisonis EV, Chernobrovkin AL, Ivanov AS, Medvedev AE, Mezentsev YV, Moshkovskii SA, Naryzhny SN, Ilina EN, Kostrjukova ES, Alexeev DG, Tyakht AV, Govorun VM, Archakov AI, Chromosome 18 transcriptome profiling and targeted proteome mapping in depleted plasma, liver tissue and HepG2 cells. J Proteome Res, 12(1):123-34(2013) [pubmed]

Keyword List

  1. curator keyword: selected reaction monitoring, SRM, targeted

Contact List

    Aleksey Filimonov
    • contact affiliation: IMSB
    • contact email: filimonov.a.d@gmail.com
    • dataset submitter:
    Alexander Archakov
    • contact affiliation: IMSB
    • contact email: alexander.archakov@ibmc.msk.ru
    • lab head:

Full Dataset Link List

  1. PeptideAtlas dataset URI
  2. PASSEL experiment URI
  3. PASSEL transition group browser URI

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