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RPXD055693-1

RPXD055693 is container for one or more analyses. The general container metadata is provided below and the table under Dataset History provides links to the various reanalyses have been provided (if any) in this container.

Reanalysis Container Summary

Title	Plasminogen deficiency exacerbates skeletal muscle loss during mechanical unloading in developing mice [Reanalysis: JPST002136]
Description	This project is “Medical proteome analysis of osteoporosis- and bone mass-related proteins using the Kibo Japanese Experiment Module of International Space Station (ISS)”. Applying proteomic technologies, this research aims to identify proteins involved in spaceflight-induced deterioration of musculo-skeletal system as well as skeletal muscle atrophy and osteoporosis occurring on the ground by searching serum, bone and skeletal muscle proteomes. The goal of this study is to get better understanding to protect the health of both astronauts and osteoporosis patients. Proteome analyses of gestrocnemius muscles from male C57BL/6J mouse (microgravity and artificial 1-g [n=6, respectively]) were carried out tryptic digestion followed by LC-MS/MS analysis (DDA). The obtained results were searched against UniProt DB by Mascot, and the identified peptides were filtered at 1% FDR threshold by searching against the decoy DB. [Original project description]
HostingRepository	jPOST
AnnounceDate	2024-09-13
AnnouncementXML	Submission_2024-09-15_01:49:44.204.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/RPXD055693
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Reanalysis of JPST002136
RepositorySupport	Supported dataset by repository
PrimarySubmitter	jPOST reanalysis
SpeciesList	scientific name: Mus musculus; NCBI TaxID: NCBITaxon:10090;
ModificationList	unknown modification; L-methionine sulfoxide; S-carboxamidomethyl-L-cysteine; N6-carbamoyl-L-lysine; alpha-aminocarbamoylated residue; Acetyl
Instrument	LTQ Orbitrap Elite

Dataset History

Reanalysis	Revision	Datetime	Status	Title / ChangeLog Entry
	0	2024-09-07 04:12:37	ID requested
0	1	2024-09-15 01:49:44	announced	Plasminogen deficiency exacerbates skeletal muscle loss during mechanical unloading in developing mice [Reanalysis: JPST002136]

Publication List

no publication

no publication

Keyword List

submitter keyword: mouse

submitter keyword: mouse

Contact List

Yasushi Ishihama
lab head
jPOST reanalysis
contact affiliation	jPOST
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003346/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003346/