PXD083958-1

PXD083958 is an original dataset announced via ProteomeXchange.

Title	Cross-platform clinical proteomics using the Charité open standard for plasma proteomics (OSPP)
Description	Based on large serum and plasma proteome studies, we generate the Charité Open Peptide Standard for Plasma Proteomics (OSPP), an open, versatile peptide internal standard for targeted and untargeted mass spectrometry-based proteomic studies. The OSPP includes 211 concentration-matched stable-isotope-labeled peptides selected for consistent quantification across a large number of plasma and serum proteome studies, and synthetic accessibility. We demonstrate the utility of OSPP in a COVID-19 inpatient cohort study for improving analytical performances, for cross-platform alignment of proteomic data, disease stratification, and biomarker discovery.
HostingRepository	iProX
AnnounceDate	2026-09-09
AnnouncementXML	Submission_2026-09-10_02:03:00.339.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ziyue Wang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	ZenoTOF 7600

Revision	Datetime	Status	ChangeLog Entry
0	2026-09-10 02:02:37	ID requested
⏵ 1	2026-09-10 02:03:01	announced

Wang Z, Farztdinov V, Sinn LR, Tober-Lau P, Ludwig D, Freiwald A, Amari F, Textoris-Taube K, Niewienda A, Welter AS, Wei AAJ, Luckau L, Kurth F, Selbach M, Hartl J, M, ü, lleder M, Ralser M, open standard for plasma proteomics (OSPP). Nat Commun, 16(1):11377(2025) [pubmed]

submitter keyword: Absolute Quantification, Biomarker Panel, COVID-19, DIA

Markus Ralser
contact affiliation	Charité – Universitätsmedizin Berlin
contact email	markus.ralser@charite.de
lab head
Ziyue Wang
contact affiliation	Charité – Universitätsmedizin Berlin
contact email	ziyue.wang@charite.de
dataset submitter

iProX dataset URI