PXD083731-1

PXD083731 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Endoplasmic Reticulum Dysfunction and Translational Deficiency in Islets of Subjects with Pre-symptomatic Stage 1 Type 1 Diabetes Revealed by Nanoproteomics Profiling
Description	Pancreata from nPOD registered donors with stage 1 pre-symptomatic type 1 diabetes (T1D) with auto-antibodies were dissected by laser microdissection (LMD) and the proteome profiles were compared to age/sex matched controls.
HostingRepository	MassIVE
AnnounceDate	2026-09-04
AnnouncementXML	Submission_2026-09-04_22:37:45.238.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Matthew Monroe
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Oxidation; Carbamidomethyl
Instrument	Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2026-09-04 20:37:31	ID requested
⏵ 1	2026-09-04 22:37:45	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: type 1 diabetes, auto-antibodies, nPOD, prediabetic, ER stress, laser microdissection, biomarkers, DatasetType:Proteomics

submitter keyword: type 1 diabetes, auto-antibodies, nPOD, prediabetic, ER stress, laser microdissection, biomarkers, DatasetType:Proteomics

Contact List

Wei-Jun Qian
contact affiliation	Pacific Northwest National Laboratory
contact email	Weijun.Qian@pnnl.gov
lab head
Matthew Monroe
contact affiliation	Pacific Northwest National Laboratory
contact email	matthew.monroe@pnnl.gov
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v14/MSV000103124/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v14/MSV000103124/