PXD083284 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Interactome of COPE protein in HeLa cells |
| Description | In this project we performed unbiased proteomics to uncover new ER-resident COPI cargo. We further filtered the results to identify proteins which are important for controlling cell growth. We identified TMEM263/C12orf23, a protein whose mutation is associated with organismal growth defects and dwarfism. Our findings demonstrate that TMEM263 is an ER-resident COPI cargo that regulates the early steps of lipid droplet formation. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-04 |
| AnnouncementXML | Submission_2026-09-04_07:23:30.747.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Nafsika Chala |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-08-27 12:01:26 | ID requested | |
| ⏵ 1 | 2026-09-04 07:23:31 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Human, COPE, TMT label, LC-MS/MS |
Contact List
| Bernadette Carroll |
|---|
| contact affiliation | School of Biochemistry and Biomedical Sciences, Faculty of Health and Life Sciences, University of Bristol, UK |
| contact email | bernadette.carroll@bristol.ac.uk |
| lab head | |
| Nafsika Chala |
|---|
| contact affiliation | University of Bristol |
| contact email | vl24245@bristol.ac.uk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD083284 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD083284
- Label: PRIDE project
- Name: Interactome of COPE protein in HeLa cells
