PXD082858 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Trypanosoma cruzi trypomastigote proteins in VPS23 hemiknockout |
| Description | We have analysed the protein composition of wild-type, a T7Cas9 strain used generate CRISPR/Cas9 deletion of VPS23 gene in Trypanosoma cruzi. The main objective was to compare the quantitative changes observed in a clone that only one copy of the gene was replaced with the parental parasite line used to make the deletion. The obtained clone presented several phenotypes both related to cell infection in vitro and animal progression of the disease. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-05 |
| AnnouncementXML | Submission_2026-09-05_06:08:32.551.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Sergio Schenkman |
| SpeciesList | scientific name: Trypanosoma cruzi Dm28c; NCBI TaxID: NEWT:1416333; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-08-19 13:21:46 | ID requested | |
| ⏵ 1 | 2026-09-05 06:08:33 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: knockout, trypomastigotes, VPS23,Trypanosoma cruzi |
Contact List
| Sergio Schenkman |
|---|
| contact affiliation | Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil |
| contact email | sschenkman@unifesp.br |
| lab head | |
| Sergio Schenkman |
|---|
| contact affiliation | Universidade Federal de São Paulo |
| contact email | sschenkman@unifesp.br |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD082858 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD082858
- Label: PRIDE project
- Name: Trypanosoma cruzi trypomastigote proteins in VPS23 hemiknockout
