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PXD082806-1

PXD082806 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIdentification and Characterization of GLRX5-Interacting Proteins in DMS114 Small Cell Lung Cancer Cells Using Co-Immunoprecipitation Coupled with Liquid Chromatography-Tandem Mass Spectrometry
DescriptionThis study was designed to identify proteins interacting with GLRX5 in small cell lung cancer cells using co-immunoprecipitation (Co-IP) coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS). DMS114 human small cell lung cancer cells were transfected with a GLRX5 overexpression construct or the corresponding negative control vector. GLRX5-associated protein complexes were immunoprecipitated from cell lysates and subsequently subjected to mass spectrometric analysis for protein identification. The proteomic data were analyzed to characterize candidate GLRX5-interacting proteins and to explore the potential molecular network associated with GLRX5 in small cell lung cancer. This dataset provides proteomic evidence for investigating the protein-protein interaction landscape of GLRX5 and its potential role in SCLC progression.
HostingRepositoryiProX
AnnounceDate2026-08-19
AnnouncementXMLSubmission_2026-08-18_19:09:25.346.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXia Gao
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-08-18 19:05:40ID requested
12026-08-18 19:09:25announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: GLRX5, protein-protein interaction, Co-IP, immunoprecipitation, mass spectrometry, interactome, proteomics, DMS114, small cell lung cancer, SCLC
Contact List
Xia Gao
contact affiliationWuhan University Renmin Hospital
contact emailgaoxia80@whu.edu.cn
lab head
Xia Gao
contact affiliationWuhan University Renmin Hospital
contact emailgaoxia80@whu.edu.cn
dataset submitter
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