PXD082799 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | An improved capillary isoelectric focusing-mass spectrometry method for characterization of monoclonal antibody charge variants |
| Description | Here, we improved the stability and enhanced separation resolution of automated cIEF-MS by bettering the quality of capillary neutral coating, reducing catholyte pH to 10 for cIEF-MS for the first time, and systematically optimizing the cIEF separation conditions for characterization of monoclonal antibody charge variants. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-19 |
| AnnouncementXML | Submission_2026-08-19_07:18:59.984.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Liangliang Sun |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | 6520A Quadrupole Time-of-Flight LC/MS |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-08-18 17:44:09 | ID requested | |
| ⏵ 1 | 2026-08-19 07:19:00 | announced | |
Publication List
| 10.1039/d1ay01556g; |
| Xu T, Han L, George Thompson AM, Sun L, An improved capillary isoelectric focusing-mass spectrometry method for high-resolution characterization of monoclonal antibody charge variants. Anal Methods, 14(4):383-393(2022) [pubmed] |
Keyword List
| submitter keyword: monoclonal antibody charge variants,cIEF-MS |
Contact List
| Liangliang Sun |
|---|
| contact affiliation | Michiagn State University |
| contact email | lsun@msu.edu |
| lab head | |
| Liangliang Sun |
|---|
| contact affiliation | Michigan State University |
| contact email | lsun@chemistry.msu.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD082799 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD082799
- Label: PRIDE project
- Name: An improved capillary isoelectric focusing-mass spectrometry method for characterization of monoclonal antibody charge variants
