PXD082602 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Multi-omics and network analysis identify SIRPA and CCL21 as central regulators of urethral scar inflammation and fibrosis |
| Description | Urethral scar is a common urological disease characterized by progressive scarring and fibrosis of the urethral wall, yet its molecular mechanisms remain poorly understood. In this study, we performed DIA-based proteomic profiling using liquid chromatography-tandem mass spectrometry (LC-MS/MS) on human urethral scar tissues (bulbar, n=3; membranous, n=3) and matched normal control tissues (n=6) to characterize the global protein expression changes associated with urethral scar formation. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-26 |
| AnnouncementXML | Submission_2026-08-25_18:22:29.923.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Chengyong Li |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-08-14 09:02:06 | ID requested | |
| ⏵ 1 | 2026-08-25 18:22:30 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Urology |
Contact List
| Chengyong Li |
|---|
| contact affiliation | Department of Urology, Second Hospital of Shanxi Medical University, Shanxi, China |
| contact email | lichengyongsdey@163.com |
| lab head | |
| Chengyong Li |
|---|
| contact affiliation | Second Hospital of Shanxi Medical University |
| contact email | lichengyongsdey@163.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD082602
- Label: PRIDE project
- Name: Multi-omics and network analysis identify SIRPA and CCL21 as central regulators of urethral scar inflammation and fibrosis
