⮝ Full datasets listing
PXD082071-1
PXD082071 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Mass spectrometry-based identification of E3 ubiquitin ligases mediating MCT1 ubiquitination |
| Description | This project aims to identify potential E3 ubiquitin ligases regulating MCT1 (monocarboxylate transporter 1) in human cells. We performed immunoprecipitation of MCT1 followed by LC-MS/MS analysis using a Q-Exactive HF X mass spectrometer. Samples included control (con) and MCT1-pulldown (MCT1) groups, each with 7 biological replicates. Proteins were identified via Mascot search against the human SwissProt database (20,324 sequences) with FDR <1% at PSM level. A total of 398–1,201 proteins were identified per sample. The results will be used to screen for candidate E3 ligases interacting with MCT1. |
| HostingRepository | iProX |
| AnnounceDate | 2026-08-03 |
| AnnouncementXML | Submission_2026-08-03_00:43:22.859.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Shuting Yang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | ubiquitination signature dipeptidyl lysine |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-08-03 00:43:02 | ID requested | |
| ⏵ 1 | 2026-08-03 00:43:23 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: ubiquitination,MCT1 |
Contact List
| Meng Zhao | |
|---|---|
| contact affiliation | Tianjin Medical University Cancer Institute & Hospital |
| contact email | zhaomeng@tmu.edu.cn |
| lab head | |
| Shuting Yang | |
| contact affiliation | Tianjin Medical University Cancer Institute & Hospital |
| contact email | yst170901@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
