PXD081816 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Human gastric extracellular matrix hydrogels maintain organoid growth and reduce gene expression associated with stemness and inflammation |
| Description | Human gastric organoids (HGOs) are 3-D cultures of primary gastric epithelial cells that serve as in vitro models for gastric epithelial physiology, development, and disease. The extracellular matrix material that organoids are maintained in provides crucial signals to the epithelial cells, regulating their function and growth. We here describe the application of human gastric ECM (hgECM) for HGO cultures, to provide a tissue- and species-specific growth matrix. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-07-29 |
| AnnouncementXML | Submission_2026-07-29_07:43:22.389.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD081816 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Michelle Cherne |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Eclipse |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-07-28 14:34:20 | ID requested | |
| ⏵ 1 | 2026-07-29 07:43:22 | announced | |
Publication List
Keyword List
| submitter keyword: decellularized tissue |
| gastric stroma |
| hydrogel |
| extracellular matrix |
Contact List
| Diane Bimczok, DVM, PhD |
|---|
| contact affiliation | Montana State University |
| contact email | diane.bimczok@montana.edu |
| lab head | |
| Michelle Cherne |
|---|
| contact affiliation | Florida Institute of Technology Department of Biomedical Engineering and Science |
| contact email | mcherne@fit.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD081816
- Label: PRIDE project
- Name: Human gastric extracellular matrix hydrogels maintain organoid growth and reduce gene expression associated with stemness and inflammation
