PXD081683-2

PXD081683 is an original dataset announced via ProteomeXchange.

Title	Dissection of In Vivo Archaeal RNA Polymerase Assembly Reveals a Modular Pathway and Stoichiometric Control
Description	These findings establish a modular and hierarchical framework for archaeal RNAP assembly, uncover key regulatory checkpoints, and demonstrate the essential role of small subunit stoichiometry. Given the shared subcomplex architecture and assembly logic, these insights not only fill a longstanding knowledge gap in archaeal RNAP assembly but also illuminate its evolutionary continuity with bacterial and eukaryotic systems and uncover regulatory vulnerabilities with potential applied relevance.
HostingRepository	iProX
AnnounceDate	2026-07-27
AnnouncementXML	Submission_2026-07-29_02:22:44.244.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Huaping Duan
SpeciesList	scientific name: Methanococcus maripaludis X1; NCBI TaxID: 1053692;
ModificationList	No PTMs are included in the dataset
Instrument	Thermo Fisher Scientific instrument model

Revision	Datetime	Status	ChangeLog Entry
0	2026-07-27 01:00:10	ID requested
1	2026-07-27 01:00:34	announced
⏵ 2	2026-07-29 02:22:45	announced	2026-07-29: Add info

Li J, Qi W, Duan H, Ren D, Liu J, Dong X, archaeal RNA polymerase assembly reveals a modular pathway and stoichiometric control. mBio, ():e0144026(2026) [pubmed]

submitter keyword: RNA polymerase, archaea, protein assembly, transcription, stoichiometry,molecular chaperones

Jie Li
contact affiliation	Institute of Microbiology, Chinese Academy of Sciences
contact email	dhp2020191498@163.com
lab head
Huaping Duan
contact affiliation	Institute of Microbiology, Chinese Academy of Sciences
contact email	dhp2020191498@163.com
dataset submitter

iProX dataset URI