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PXD081434-1

PXD081434 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomics reveals protein signatures and steroidogenic pathways underlying gonadal sex differentiation in Sinonovacula constricta
DescriptionThe razor clam Sinonovacula constricta is an economically important cultured mollusk in China, but the molecular mechanism of its gonadal development and sexual differentiation remains unclear. In this study, proteomic analysis of gonadal tissues was performed to identify key sex‑biased proteins. A total of 3,217 differentially expressed proteins (DEPs) were detected between testes and ovaries. Among these, members of the Tektin family, Ropporin‑1, and Tssk proteins were significantly upregulated in the testis, whereas Histone H1 and FAT4 showed elevated expression in the ovary. These sex‑specific protein signatures suggest that structural components of flagellar motility (Tektins, Ropporin‑1) and spermatogenesis‑related kinases (Tssk) are preferentially enriched in the male gonad, while chromatin‑associated proteins (Histone H1) and atypical cadherins (FAT4) are more prominent in the ovary. Our proteomic dataset provides a comprehensive protein‑level resource for understanding gonadal development and sexual differentiation in S. constricta, and highlights candidate protein markers for future reproductive and breeding studies.
HostingRepositoryiProX
AnnounceDate2026-07-21
AnnouncementXMLSubmission_2026-08-31_20:17:15.031.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHanHan Yao
SpeciesList scientific name: Sinonovacula constricta; NCBI TaxID: 98310;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 480; Q Exactive HF-X; timsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-07-21 19:42:40ID requested
12026-08-31 20:17:15announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Sinonovacula constricta, protein
Contact List
HanHan Yao
contact affiliationZhejiang Wanli University
contact emailyaohanhan1020@126.com
lab head
HanHan Yao
contact affiliationZhejiang Wanli University
contact email1907763228@qq.com
dataset submitter
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iProX dataset URI