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PXD081423-1

PXD081423 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleNicotinamide mononucleotide combined glucose counteracts iron overload induced mitochondrial dysfunction in mice under hypobaric hypoxia
DescriptionExtreme high-altitude environment poses severe threats to human health, underscoring the urgent need for effective, safe metabolic interventions.Overall, our work provides a systems-level atlas, uncovering an unidentified mechanism in which NMN and glucose mitigate iron-mediated oxidative stress independent of ferroptosis, and offering a potential therapeutic strategy for high-altitude hypoxia.
HostingRepositoryiProX
AnnounceDate2026-07-20
AnnouncementXMLSubmission_2026-07-21_19:17:41.291.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJun Zeng
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Eclipse
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-07-21 19:17:23ID requested
12026-07-21 19:17:41announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Nicotinamide mononucleotide, hypobaric hypoxia
Contact List
Jun Zeng
contact affiliationJimei University
contact emailjunzeng@jmu.edu.cn
lab head
Jun Zeng
contact affiliationJimei University
contact emailjunzeng@jmu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI