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PXD081029-1

PXD081029 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic profiling of ischemic penumbral tissue after head-down positioning intervention in a rat model of ischemic stroke
DescriptionIschemic stroke is a major cause of neurological disability. Head-down positioning (HDP) has been proposed as a simple non-pharmacological intervention to improve cerebral perfusion after ischemic stroke. In this study, label-free quantitative proteomics was performed to characterize protein alterations associated with ischemic injury and HDP-mediated neuroprotection. Ischemic penumbral tissues were collected from male Sprague-Dawley rats subjected to middle cerebral artery occlusion (MCAO) followed by HDP intervention.
HostingRepositoryiProX
AnnounceDate2026-07-14
AnnouncementXMLSubmission_2026-07-14_00:43:49.429.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYaoyuan Cui
SpeciesList scientific name: Rattus rattus; NCBI TaxID: 10117;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-07-14 00:42:54ID requested
12026-07-14 00:43:49announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Ischemic stroke, Head-down positioning, Neuroprotection, Blood-brain barrier, Cytoskeletal remodeling
Contact List
Yujuan Li
contact affiliationBeijing Institute of Technology
contact emailLylyjlzh2006@163.com
lab head
Yaoyuan Cui
contact affiliationBeijing Institute of Technology
contact emailcuiyaoyuan7370@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI