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PXD081020-1

PXD081020 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic Profiling of Left Ventricular Myocardium in a High-Fat Diet and STZ-Induced Mouse Model of Diabetic Cardiomyopathy
DescriptionThis project investigates protein expression alterations in the left ventricular myocardium of a high-fat diet and streptozotocin-induced mouse model of diabetic cardiomyopathy. Proteomic analysis was performed using data-independent acquisition LC–MS/MS on an Orbitrap Exploris 480 platform. Raw data were processed with Spectronaut, and differentially expressed proteins were identified using fold-change and multiple-testing-adjusted significance thresholds.
HostingRepositoryiProX
AnnounceDate2026-07-13
AnnouncementXMLSubmission_2026-07-19_20:31:44.921.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFeng Zhang
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Astral
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-07-14 00:17:42ID requested
12026-07-19 20:31:45announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Diabetic cardiomyopathy, proteomics, left ventricular myocardium, high-fat diet, streptozotocin, DIA mass spectrometry, Orbitrap Exploris 480, differentially expressed proteins, functional annotation
Contact List
Zhuqing Li
contact affiliationTianjin First Central Hospital
contact emaildinger326@126.com
lab head
Feng Zhang
contact affiliationTianjin First Central Hospital
contact emailfengzhang0222@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI