⮝ Full datasets listing
PXD080975-1
PXD080975 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | TMT10 quantitative proteomic analysis of depleted neonatal cerebrospinal fluid from infants with hydrocephalus and controls |
| Description | This dataset contains TMT10 quantitative tandem mass spectrometry data from depleted neonatal cerebrospinal fluid samples, including hydrocephalus cases and controls. Samples were multiplexed using TMT channels with reference-pool channels included across runs. The original search parameters used Homo sapiens taxonomy, SwissProt plus cRAP contaminant FASTA databases, Trypsin/P digestion with up to 4 missed cleavages, 20 ppm precursor mass tolerance, 0.02 Da fragment mass tolerance, fixed carbamidomethylation of cysteine, fixed TMT labeling of peptide N-termini and lysine residues, and variable oxidation of methionine, protein N-terminal acetylation, asparagine deamidation, and N-terminal glutamine to pyroglutamate conversion. The submitted files include original Thermo RAW files, MGF peak lists, mzIdentML search results, TMT channel/sample metadata, search parameters, and derived PSM/quantification tables. |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-07-13 |
| AnnouncementXML | Submission_2026-07-13_09:00:00.667.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Cheryl Lichti |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | S-carboxamidomethyl-L-cysteine; Acetyl; TMT6plex; deamidated L-asparagine; Gln->pyro-Glu; L-methionine sulfoxide |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-07-13 08:14:45 | ID requested | |
| ⏵ 1 | 2026-07-13 09:00:01 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: human, cerebrospinal fluid, CSF, neonatal, infant, hydrocephalus, post-hemorrhagic hydrocephalus, congenital hydrocephalus, TMT10, TMT 10plex, quantitative proteomics, tandem mass spectrometry, shotgun proteomics, Q Exactive, SwissProt, cRAP, DatasetType:Proteomics |
Contact List
| Albert Isaacs, MD, PHD | |
|---|---|
| contact affiliation | Nationwide Children's Hospital |
| contact email | Albert.Isaacs@nationwidechildrens.org |
| lab head | |
| Cheryl Lichti | |
| contact affiliation | Washington University in St. Louis |
| contact email | clichti@wustl.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v13/MSV000102463/ |
