PXD080876 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Protein restriction reprograms the multi-organ proteomic landscape of mouse aging |
| Description | We conducted an extensive study involving the collection of 41 mouse organs at eight distinct time points spanning the mouse lifespan and implemented a dietary intervention with varying protein intake for different age and sex groups. We also obtained plasma samples from both mice and humans to investigate the systemic effects of aging and PR. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-07-13 |
| AnnouncementXML | Submission_2026-07-12_16:39:25.419.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Tian Lu |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-07-10 16:21:46 | ID requested | |
| ⏵ 1 | 2026-07-12 16:39:26 | announced | |
Publication List
| Lu T, Xie Y, Wang Y, Lin X, Cai X, Zhang Y, Nie Z, Su C, Gou W, Zhang H, Wang J, Zhong Y, Lai Z, Xiang J, Shan PF, Zheng JS, Wang H, Zhu Y, Guo T, Protein restriction reprograms the multi-organ proteomic landscape of mouse aging. Cell, 188(25):7309-7326.e20(2025) [pubmed] |
| 10.1016/j.cell.2025.10.004; |
Keyword List
| submitter keyword: DDA files for library generation |
Contact List
| Tiannan Guo |
|---|
| contact affiliation | 1 Affiliated Hangzhou First People’s Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, School of Future Biomedicine, Westlake University, Hangzhou, Zhejiang Province, China. 2 Westlake Center for Intelligent Proteomics, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang Province, China. 3 Research Center for Industries of the Future, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province, China. |
| contact email | guotiannan@westlake.edu.cn |
| lab head | |
| Tian Lu |
|---|
| contact affiliation | Westlake University |
| contact email | lutian@westlake.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD080876 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD080876
- Label: PRIDE project
- Name: Protein restriction reprograms the multi-organ proteomic landscape of mouse aging
