PXD080702-1

PXD080702 is an original dataset announced via ProteomeXchange.

Title	Coffee remodels the histone acetylation landscape in association with suppression of the MYC transcriptional program
Description	This dataset contains data-independent acquisition (DIA) proteomics data generated from K562 human leukemia cells treated with coffee extract or vehicle control. Quantitative proteomic analysis was performed to investigate molecular mechanisms underlying coffee-induced epigenetic remodeling. The proteomics dataset was integrated with histone modification profiling, ChIP-seq and RNA-seq analyses to characterize pathways associated with histone acetylation and MYC transcriptional regulation.
HostingRepository	jPOST
AnnounceDate	2026-07-08
AnnouncementXML	Submission_2026-07-07_23:30:07.484.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kazumasa Aoyama
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	unknown modification; N6-biotinyl-L-lysine
Instrument	instrument

Revision	Datetime	Status	ChangeLog Entry
0	2026-07-07 23:30:04	ID requested
⏵ 1	2026-07-07 23:30:07	announced

Dataset with its publication pending

submitter keyword: Coffee, histone acetylation, H3K27ac, MYC, DIA proteomics, K562

Kazumasa Aoyama
lab head
Kazumasa Aoyama
contact affiliation	Division of Hygienic Chemistry, Faculty of Pharmacy, Keio University
dataset submitter

jPOST dataset URI

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST004748/