PXD080644-1

PXD080644 is an original dataset announced via ProteomeXchange.

Title	Identification of the ACTL8 interactome using immunoprecipitation-mass spectrometry
Description	Immunoprecipitation coupled with mass spectrometry (IP-MS) was performed to identify proteins interacting with ACTL8 in human cells. Cell lysates were immunoprecipitated using an anti-ACTL8 antibody or IgG control, followed by LC-MS/MS analysis on a Q Exactive HF Orbitrap mass spectrometer. Protein abundance was estimated based on peptide-spectrum matches (PSMs). Proteins enriched more than two-fold in ACTL8 immunoprecipitates compared with IgG controls and with p < 0.05 were considered high-confidence ACTL8-interacting proteins.
HostingRepository	iProX
AnnounceDate	2026-07-06
AnnouncementXML	Submission_2026-07-06_23:44:52.518.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qin Yang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2026-07-06 23:43:34	ID requested
⏵ 1	2026-07-06 23:44:53	announced

Dataset with its publication pending

submitter keyword: ACTL8, Immunoprecipitation, IP-MS, Homo sapiens

Lei Ming
contact affiliation	Shanghai Institute of Precision Medicine, Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine
contact email	leim@shsmu.edu.cn
lab head
Qin Yang
contact affiliation	Shanghai Institute of Precision Medicine, Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine
contact email	yangqin@shsmu.edu.cn
dataset submitter

iProX dataset URI