PXD080534-1

PXD080534 is an original dataset announced via ProteomeXchange.

Title	Targeted metabolomics (LC-MS/MS) of VPA-ASD mouse feces: prebiotic intervention study
Description	This subproject contains targeted metabolomics raw data (mzML format) and processed quantification results from fecal samples of a valproic acid (VPA)-induced mouse model of autism spectrum disorder (ASD). The study includes three groups: control, VPA-exposed ASD model, and VPA-exposed mice treated with a prebiotic. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was performed to quantify neurotransmitters and related metabolites. These data are part of a larger study investigating the gut-brain axis mechanism underlying prebiotic-mediated behavioral rescue.
HostingRepository	iProX
AnnounceDate	2026-07-02
AnnouncementXML	Submission_2026-07-03_02:45:03.820.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Meng Sun
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	4800 Plus MALDI TOF/TOF; 5800 TOF/TOF

Revision	Datetime	Status	ChangeLog Entry
0	2026-07-03 02:44:26	ID requested
⏵ 1	2026-07-03 02:45:04	announced

Dataset with its publication pending

submitter keyword: Targeted metabolomics, ASD, VPA, mouse model, prebiotic, gut-brain axis, feces

Jianhong Luo
contact affiliation	School of Brain Science and Brain Medicine, Zhejiang University School of Medicine
contact email	luojianhong@zju.edu.cn
lab head
Meng Sun
contact affiliation	School of Brain Science and Brain Medicine, Zhejiang University School of Medicine
contact email	3479284181@qq.com
dataset submitter

iProX dataset URI