PXD080124-1

PXD080124 is an original dataset announced via ProteomeXchange.

Title	Probing protein dynamics in inducible nitric oxide synthase by photoactivated cross-linking mass spectrometry
Description	Quantitative XL-MS using sulfo-SDA, a heterobifunctional cross-linker with ultrafast broad residue reactivity upon UV-triggered carbene formation, to study E546N mutation-dependent decreases in specific inter-subunit FMN–heme cross-links in human inducible NOS (iNOS).
HostingRepository	PRIDE
AnnounceDate	2026-09-09
AnnouncementXML	Submission_2026-09-09_09:42:06.439.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ting Jiang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	iodoacetamide derivatized residue
Instrument	timsTOF fleX MALDI-2

Revision	Datetime	Status	ChangeLog Entry
0	2026-06-24 09:11:48	ID requested
⏵ 1	2026-09-09 09:42:06	announced

10.1021/ACS.BIOCHEM.6C00511;

submitter keyword: photoactivated,XL-MS, NOS

Changjian Feng
contact affiliation	UNM
contact email	cfeng@unm.edu
lab head
Ting Jiang
contact affiliation	UNM
contact email	tjiang@salud.unm.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD080124

PRIDE project URI

• PRIDE
  1. PXD080124
     1. Label: PRIDE project
     2. Name: Probing protein dynamics in inducible nitric oxide synthase by photoactivated cross-linking mass spectrometry