PXD079927 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Immune Complex-Induced Migration of Slan+ Non-Classical Monocytes |
| Description | Slan+ Non-Classical Monocytes migrate on immobilized immune complexes. This phenomenon can be blcoked with anti-CD16 blocking antibodies and is therefore thought to be mediated via CD16 (FcyRIII). Nonetheless, other CD16+ cells, such as NK cells or neutrophils, as well as lineage related cells suchs as classical monocytes do not migrate on immobilized immune complexes. We therefore isolated protein content of Slan+ Non-Classical Monocytes after migration immobilized immune complexes to perform phosphoproteomics in order to better understand the underlying signaling pathways inducing the migratory response. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-07-09 |
| AnnouncementXML | Submission_2026-07-09_00:14:58.707.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Frank Stein |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-06-19 09:09:55 | ID requested | |
| ⏵ 1 | 2026-07-09 00:14:59 | announced | |
Publication List
| 10.1016/J.JAUT.2026.103579; |
| 10.1016/j.jaut.2026.103579; |
| Hertwig M, Oehrl S, D, ö, bel T, Zhang H, Meisel S, List A, Sch, ä, kel K, non-classical monocytes. J Autoimmun, 162():103579(2026) [pubmed] |
Keyword List
| submitter keyword: SlanMo, CD16a,Immune Complexes, FcyRIIIa, Migration, Slan+ Non-Classical Monocytes, Haptokinesis |
Contact List
| Knut Schäkel |
|---|
| contact affiliation | Universitäts Hautklinik Heidelberg |
| contact email | Knut.Schaekel@med.uni-heidelberg.de |
| lab head | |
| Frank Stein |
|---|
| contact affiliation | EMBL |
| contact email | frank.stein@embl.de |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD079927 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD079927
- Label: PRIDE project
- Name: Immune Complex-Induced Migration of Slan+ Non-Classical Monocytes
