PXD079895 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Identification of tau-isoforms in muscle by IP-PRM-MS |
| Description | Blood p-tau217 has emerged as an accurate biomarker of Alzheimer’s disease (AD) pathology but is also elevated in amyotrophic lateral sclerosis (ALS), likely reflecting confounding contributions from peripheral tau released from denervated muscle fibres. Thus, assays selectively measuring brain-derived (BD) tau and BD-p-tau217 may improve diagnostic specificity. Here we analyzed the composition of tau isoforms in muscle tissue after pan-tau-IP including isoforms with exon 4a-long |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-04 |
| AnnouncementXML | Submission_2026-09-04_01:47:19.162.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Henning Großkopf |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-06-18 13:37:42 | ID requested | |
| ⏵ 1 | 2026-09-04 01:47:19 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: isoform, PRM, IP-MS,tau |
Contact List
| Prof. Dr. Markus Otto |
|---|
| contact affiliation | Department of Neurology, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany |
| contact email | markus.otto@uk-halle.de |
| lab head | |
| Henning Großkopf |
|---|
| contact affiliation | Department of Neurology, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany |
| contact email | henning.grosskopf@uk-halle.de |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD079895 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD079895
- Label: PRIDE project
- Name: Identification of tau-isoforms in muscle by IP-PRM-MS
