PXD079432 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | MS-based proteomic analysis of TgGCN5b-dependent acetylome and proteome |
| Description | Histone acetylation, a fundamental epigenetic mechanism that controls gene activity, is essential for the developmental plasticity and virulence of the parasite Toxoplasma gondii. However, how this parasite organizes and deploys its acetyltransferase machinery has remained unclear. We show that T. gondii rewired this process using a plant-like system built around the acetyltransferase TgGCN5b, which differs from the typical SAGA complex found in other eukaryotes. We evaluated the impact of TgGCN5b depletion on lysine acetylome and total proteome of infecting parasites. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-07-25 |
| AnnouncementXML | Submission_2026-07-25_06:31:40.251.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD079432 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Yohann Couté |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; scientific name: Toxoplasma gondii; NCBI TaxID: NEWT:5811; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Exploris 480; Orbitrap Ascend |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-06-09 00:12:02 | ID requested | |
| ⏵ 1 | 2026-07-25 06:31:40 | announced | |
Publication List
Keyword List
| submitter keyword: Toxoplasma, TgGCN5b, acetylation, nanoLC-MS/MS |
Contact List
| Yohann Couté |
|---|
| contact affiliation | EDyP |
| contact email | yohann.coute@cea.fr |
| lab head | |
| Yohann Couté |
|---|
| contact affiliation | EDyP |
| contact email | yohann.coute@cea.fr |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD079432 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD079432
- Label: PRIDE project
- Name: MS-based proteomic analysis of TgGCN5b-dependent acetylome and proteome
