PXD079313 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Systematic mapping of MEK (MEK1, MEK2) interactomes, in WT, inactive, clinically relevant and functional mutations |
| Description | This dataset provides a comprehensive proteomic map of the MEK1 and MEK2 interactomes, utilizing two complementary mass spectrometry (MS) approaches to capture both stable and transient protein-protein interactions (PPIs). A total of 8 functional and clinical mutations of MEK1 was used as bait in addition to the WT. For MEK2, only the WT was used. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-07-10 |
| AnnouncementXML | Submission_2026-07-10_03:14:38.932.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Markus Hartl |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-06-05 05:25:13 | ID requested | |
| ⏵ 1 | 2026-07-10 03:14:39 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: AP-MS, MAPK pathway, proximity dependent labeling,RAS/RAF/MEK/ERK, TurboID, disease mutations, MEK1, MEK2, HEK293T, protein-protein interactions |
Contact List
| Prof. Dr. Manuela Baccarini |
|---|
| contact affiliation | Max Perutz Labs, Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology, University of Vienna |
| contact email | Manuela.baccarini@univie.ac.at |
| lab head | |
| Markus Hartl |
|---|
| contact affiliation | Max Perutz Labs, Mass Spectrometry Facility, Vienna Biocenter Campus (VBC), Dr. Bohr-Gasse 9, Vienna, Austria |
| contact email | proteomics@maxperutzlabs.ac.at |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD079313 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD079313
- Label: PRIDE project
- Name: Systematic mapping of MEK (MEK1, MEK2) interactomes, in WT, inactive, clinically relevant and functional mutations
