PXD079248-1

PXD079248 is an original dataset announced via ProteomeXchange.

Title	The profiling of bile acid-inducing proteins in Streptomyces microflavus
Description	To further investigate the potential functions of Streptomyces in the gut, the bile acid-induction experiment was conducted utilizing mass spectrometry for identification. Bile acids (BAs), crucial primary metabolites of cholesterol metabolism, play a vital role in lipid digestion and absorption, enterohepatic circulation, and metabolic regulation. Notably, elevated intestinal bile acid levels are observed during high-fat diet consumption. In the present study, Streptomyces microflavus was stimulated with four distinct bile acids: CA, DCA, CDCA, and UDCA. Subsequently, bacterial cells were harvested, proteins extracted, and data-independent acquisition (DIA)-based proteomic identification performed.
HostingRepository	iProX
AnnounceDate	2026-06-03
AnnouncementXML	Submission_2026-06-03_19:26:48.780.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jinlong Wang
SpeciesList	scientific name: Streptomyces microflavus; NCBI TaxID: 1919;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2026-06-03 19:26:27	ID requested
⏵ 1	2026-06-03 19:26:49	announced

Dataset with its publication pending

submitter keyword: Bile acid, Streptomyces microflavus, Proteomics

Jinlong Wang
contact affiliation	Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences
contact email	jinlongwang@ucas.ac.cn
lab head
Jinlong Wang
contact affiliation	Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences
contact email	jinlongwang@ucas.ac.cn
dataset submitter

iProX dataset URI