PXD079157-1

PXD079157 is an original dataset announced via ProteomeXchange.

Title	Proteomic profiling of low-abundance serum proteins in depression: a dataset from LC-MS/MS analysis
Description	Depression is a common mental disorder with complex pathophysiology, and serum proteomics offers a promising approach to discover potential biomarkers. However, the wide dynamic range of serum proteins, particularly the dominance of high-abundance proteins, often masks low-abundance components that may carry key pathological information. In this study, we performed a serum proteomic analysis focusing on low-abundance fractions in individuals with depression. A total of 211 serum samples were collected from patients diagnosed with depression and healthy controls. This dataset provides a valuable resource for understanding the molecular mechanisms of depression and may facilitate the discovery of low-abundance serum protein biomarkers. The data can be reanalyzed for protein–protein interaction networks, pathway enrichment, or comparison with other psychiatric disorders.
HostingRepository	iProX
AnnounceDate	2026-06-01
AnnouncementXML	Submission_2026-06-01_19:54:38.017.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wenmin Tian
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2026-06-01 19:54:10	ID requested
⏵ 1	2026-06-01 19:54:38	announced

Dataset with its publication pending

submitter keyword: Serum proteomics, Low-abundance proteins

Yang Chen
contact affiliation	The Center for Precision Medicine Multi-omics Research (CPMMR)
contact email	chenyang1816185048@bjmu.edu.cn
lab head
Wenmin Tian
contact affiliation	The Center for Precision Medicine Multi-omics Research (CPMMR)
contact email	tianwenmin2019@126.com
dataset submitter

iProX dataset URI