PXD079129 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | From stem cells to somites: revealing genetic and exogenous factors of human embryogenesis |
| Description | In this project, we characterized the temporal dynamics of protein expression during the differentiation of human iPSCs to somitoids, stem cell–derived 3D models that recapitulate early embryonic somitogenesis. Using quantitative time-course proteomics, we captured how protein abundance changed as pluripotent stem cells progressed into segmented, organized structures, providing insight into the molecular processes underlying human axial development. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-07 |
| AnnouncementXML | Submission_2026-08-07_02:29:06.397.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | S Stelloo |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-06-01 06:57:16 | ID requested | |
| ⏵ 1 | 2026-08-07 02:29:07 | announced | |
Publication List
| 10.1016/j.stemcr.2026.103023; |
| Alejo-Vinogradova MT, Str, ø, m YE, Lamers LA, Chang YW, Hendriksen MJ, Moosajee M, Vermeulen M, Stelloo S, From stem cells to somites: Revealing genetic and exogenous factors of human embryogenesis. Stem Cell Reports, ():103023(2026) [pubmed] |
Keyword List
| submitter keyword: matrigel, iPSCs,human somitoids, proteomics, somitogenesis |
Contact List
| Suzan Stelloo |
|---|
| contact affiliation | Department of Urology, Radboud Institute for Medical Innovation, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA, Nijmegen, The Netherlands. |
| contact email | suzan.stelloo@radboudumc.nl |
| lab head | |
| S Stelloo |
|---|
| contact affiliation | Department of Urology, Radboud University Medical Center (RUMC), Nijmegen, The Netherlands |
| contact email | stelloo@science.ru.nl |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD079129 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD079129
- Label: PRIDE project
- Name: From stem cells to somites: revealing genetic and exogenous factors of human embryogenesis
