PXD078654-1

PXD078654 is an original dataset announced via ProteomeXchange.

Title	4D-Label-free quantitative proteomic analysis of differential proteins in the lung tissues of AT2 cell-specific VDR knockout mice
Description	Six-week-old control mice and VDR CKO mice were administered tamoxifen (100 mg/kg body weight) via intraperitoneal injection once daily for five consecutive days. After a two-week interval, mice of each genotype were randomly allocated into two groups: the saline group and the BLM group. On day 0, mice in the BLM subgroup received an intratracheal injection of BLM (1 mg/kg), while those in the saline subgroup were given an equivalent volume of saline via intratracheal injection. All mice were euthanized on day 21, and their lungs were harvested for 4D label-free quantitative proteomics analysis.
HostingRepository	iProX
AnnounceDate	2026-05-20
AnnouncementXML	Submission_2026-05-21_00:23:24.101.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zili Zhou
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2026-05-21 00:22:09	ID requested
⏵ 1	2026-05-21 00:23:24	announced

Dataset with its publication pending

submitter keyword: 4D label-free quantitative proteomics, Lung fibrosis, Vitamin D receptor, Alveolar type 2 cells

Shaoxi Cai
contact affiliation	Nanfang Hospital, Southern Medical University
contact email	hxkc@smu.edu.cn
lab head
Zili Zhou
contact affiliation	Nanfang Hospital, Southern Medical University
contact email	zhouzili123@smu.edu.cn
dataset submitter

iProX dataset URI