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PXD078554-2

PXD078554 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQualitative assessment of nasopharyngeal aspirates as an alternative to tracheal aspirates in extremely preterm infants
DescriptionThe search for novel biomarkers for respiratory diseases, especially those associated with extreme premature birth, has been a challenge over the past several decades. In this study, we performed a qualitative comparison of proteomic profiles derived from a novel noninvasive sampling methodology, nasopharyngeal aspiration, and an established invasive methodology, tracheal aspiration, in preterm neonates, to determine whether nasopharyngeal aspirates (NPAs) are suitable for respiratory biomarker research. Paired NPA and tracheal aspirate (TA) samples (N=5) were collected from 1-week-old neonates and analyzed via high-throughput proteomics. The shared and specific sample proteins were studied. Shared and sample-specific proteins were analyzed using state-of-the-art enrichment analyses to evaluate lung tissue specificity and proteomic similarity.
HostingRepositoryPRIDE
AnnounceDate2026-06-11
AnnouncementXMLSubmission_2026-06-11_01:14:50.001.xml
DigitalObjectIdentifierhttps://doi.org/10.6019/PXD078554
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterFernando Garrido-Muñoz
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-05-19 07:31:55ID requested
12026-06-11 01:12:37announced
22026-06-11 01:14:50announced2026-06-11: Updated project metadata.
Publication List
10.6019/PXD078554;
10.3389/fped.2026.1804309;
Keyword List
submitter keyword: Neonate,Lung Diseases, Bronchopulmonary dysplasia, Proteomics, Data Collection, Computational Biology
Contact List
Almudena Alonso-Ojembarrena
contact affiliationNeonatal Intensive Care Unit. Puerta del Mar University Hospital, Cádiz (Spain)
contact emailalmudena.alonso.sspa@juntadeandalucia.es
lab head
Fernando Garrido-Muñoz
contact affiliationInstituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain
contact emailfgarrido-ibis@us.es
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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