PXD078482 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | LC-MS/MS analysis of MAVS-interacting proteins in H1N1-infected A549 cells with ALOX15 overexpression |
| Description | To identify the key molecules involved in ALOX15-mediated K63-linked ubiquitination of MAVS, we performed LC-MS/MS-based proteomics analysis of MAVS-interacting proteins in H1N1-infected A549 cells transfected with Flag-ALOX15 or plasmid vector. This analysis identified USP19, a deubiquitinase, as a potential candidate, as its interaction with MAVS was significantly reduced in ALOX15-overexpressing cells. This suggests that ALOX15 and USP19 might compete for binding to MAVS. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-07-03 |
| AnnouncementXML | Submission_2026-07-03_01:47:49.168.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Shu-Hua Ouyang |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-05-18 03:03:24 | ID requested | |
| ⏵ 1 | 2026-07-03 01:47:49 | announced | |
Publication List
Keyword List
| submitter keyword: USP19, virus,ALOX15, MAVS, ubiquitination, deubiquitinase, LC-MS/MS |
Contact List
| Yi-Fang Li |
|---|
| contact affiliation | Jinan University, China |
| contact email | liyifang706@jnu.edu.cn |
| lab head | |
| Shu-Hua Ouyang |
|---|
| contact affiliation | Jinan University |
| contact email | shouyang@jnu.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD078482 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD078482
- Label: PRIDE project
- Name: LC-MS/MS analysis of MAVS-interacting proteins in H1N1-infected A549 cells with ALOX15 overexpression
