PXD078467-1

PXD078467 is an original dataset announced via ProteomeXchange.

Title	Plasma Proteomic Analysis in Extremely Premature Infants with Brain Injury
Description	Brain injury in extremely premature infants (gestational age <32 weeks) causes lifelong neurological sequelae, but the differentially expressed plasma proteins remains unclear. Nineteen extremely premature infants were enrolled, including 10 with brain injury and 9 without brain injury. Plasma proteomic sequencing were performed. Differential proteins were identified using t test analysis, followed by enrichment analyses. univariate logistic regression and LASSO were applied to identify informative clinical variables. Forty-four differential proteins were identified, which were mainly enriched in cytoskeleton-related functions. Four hub characteristic proteins were screened, including phosphoglycerate kinase 2 (PGK2), metallothionein, C-myc promoter-binding protein (MYCPP), and peroxisomal trans-2-enoyl-CoA reductase (PECR).
HostingRepository	iProX
AnnounceDate	2026-05-18
AnnouncementXML	Submission_2026-05-18_00:54:56.355.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Aihua Cao
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF HT

Revision	Datetime	Status	ChangeLog Entry
0	2026-05-18 00:54:09	ID requested
⏵ 1	2026-05-18 00:54:56	announced

Dataset with its publication pending

submitter keyword: Extremely premature infants, brain injury

plasma proteins

Aihua Cao
contact affiliation	Qilu Hospital of Shandong University, Jinan, China
contact email	qlyyebk@163.com
lab head
Aihua Cao
contact affiliation	Qilu Hospital of Shandong University, Jinan, China
contact email	qlyyebk@163.com
dataset submitter

iProX dataset URI